NSDNA: The Nervous System Disease NcRNAome Atlas

Details

Disease Name	Neuroblastoma
Nocoding RNA Name	MALAT1
Expression Pattern	associated
Species	Homo sapiens
Detection Methods	DNA microarray,transfection,Northern Blot,in situ hybridization,immunochemistry etc.
Target	N/A
Tissue	neuroblastoma cell lines
Treatment	N/A
PubMed ID	20729808
Year	2010
Detail Description	DNA microarray analysis in Malat1-depleted neuroblastoma cells indicates that Malat1 controls the expression of genes involved not only in nuclear processes, but also in synapse function. In cultured hippocampal neurons, knock-down of Malat1 decreases synaptic density, whereas its over-expression results in a cell-autonomous increase in synaptic density.

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