Details
Disease Name Glioblastoma
Nocoding RNA Name MEG3
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Real-time PCR,Flow Cytometry,RNA immunoprecipitation,Luciferase Reporter Assay etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 22234798
Year 2012
Detail Description MEG3 expression was markedly decreased in glioma tissues compared with adjacent normal tissues. Moreover, ectopic expression of MEG3 inhibited cell proliferation and promoted cell apoptosis in U251 and U87 MG human glioma cell lines. We further verified that MEG3 was associated with p53 and that this association was required for p53 activation.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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