| Disease Name |
Glioblastoma |
| Nocoding RNA Name |
MEG3 |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
Helicos single molecule sequencing,RT-qPCR etc. |
| Target |
N/A |
| Tissue |
glioblastoma cell lines |
| Treatment |
I-BET151
|
| PubMed ID |
26111795 |
| Year |
2015 |
| Detail Description |
I-BET151 induced a statistically significant up-regulation of GBM down-regulated lncRNAs including MEG3, NEAT1 (nuclear paraspeckle assembly transcript,and DGCR5. By contrast, this treatment yielded downregulation of GBM up-regulated lncRNAs HOTAIRM1, TUG1(taurine up-regulated 1), and H19 (imprinted maternally expressed transcript). |
|