Details
Disease Name Glioma
Nocoding RNA Name MEG3
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Real-time quantitative PCR,Western Blot,Methylation-specific polymerase chain reaction etc.
Target N/A
Tissue brain
Treatment N/A
PubMed ID 26676363
Year 2015
Detail Description downregulation of MEG3 expression due to hypermethylation of MEG3 was observed in gliomas tissues. Treatment of glioma cells with the DNA methylation inhibitor 5-Aza-2'-deoxycytidine (5-AzadC) decreased aberrant hypermethylation of the MEG3 promoter and prevented the loss of MEG3 expression.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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