| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | MIR155HG |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray etc. |
| Target | N/A |
| Tissue | surgically resected glioma samples |
| Treatment | N/A |
| PubMed ID | 28371892 |
| Year | 2017 |
| Detail Description | Increased MIR155HG was associated with glioma grade, mesenchymal transition, and poor prognosis. Bioinformatics and luciferase reporter assays revealed that protocadherin 9 and protocadherin 7, which act as tumor suppressors by inhibiting the Wnt/β-catenin pathway, were direct targets of miR-155-5p and miR-155-3p, respectively. Finally, we identifed NSC141562 as a potent small-molecule inhibitor of the MIR155HG/miR-155 axis. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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