Details
Disease Name Neuroblastoma
Nocoding RNA Name NDM29
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time quantitative RT-PCR,RNAi,MTT assay etc.
Target N/A
Tissue neuroblastoma cell lines
Treatment N/A
PubMed ID 20581224
Year 2010
Detail Description the synthesis of a pol III-transcribed noncoding (nc) RNA (NDM29) strongly restricts NB development by promoting cell differentiation, a drop of malignancy processes, and a dramatic reduction of the tumor initiating cell (TIC) fraction in the NB cell population. Notably, the overexpression of NDM29 also confers to malignant NB cells an unpredicted susceptibility to the effects of antiblastic drugs used in NB therapy.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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