Details
Disease Name Glioblastoma
Nocoding RNA Name PCAT-1
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR etc.
Target N/A
Tissue GBM cell lines
Treatment N/A
PubMed ID 27306825
Year 2016
Detail Description Expression profiles of 83 lncRNA genes were analyzed for a significant dysregulation, compared to the control cells. Among lncRNAs, 51 lncRNA genes down-regulated, while 8 lncRNA genes were up-regulated. PCAT-1, MEG3, HOTAIR lncRNAs showed low expression in glioblastoma compared to the human (parental) brain cancer stem cells, indicating their role as tumour suppressor genes on gliomas.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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