Details
Disease Name Glioma
Nocoding RNA Name PVT1
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Western Blot,Luciferase Reporter Assay,immunohistochemistry etc.
Target Atg7
Tissue surgically resected glioma samples
Treatment N/A
PubMed ID 28351322
Year 2017
Detail Description The long non-coding RNA PVT1 was found to be highly expressed in glioma vascular endothelial cells. PVT1 overexpression increased the expression of Atg7 and Beclin1 by targeting miR-186, which induced protective autophagy, thus promoting glioma vascular endothelial cell proliferation, migration, and angiogenesis.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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