Details
Disease Name Neuroblastoma
Nocoding RNA Name T-UC.300A
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR,Western Blot,siRNA knockdown,Cell proliferation assay etc.
Target N/A
Tissue neuroblastoma cell lines (SH-SY5Y, SK-N-BE, LAN-5)
Treatment N/A
PubMed ID 23565812
Year 2013
Detail Description T-UC.300A, an independent transcript whose expression is down-regulated following ATRA was achieved by siRNA knockdown, resulting in the decreased viability and invasiveness of ATRA-responsive cell lines. Gene expression microarray analysis following knockdown of T-UC.300A revealed a number of genes whose expression was altered by changing T-UC.300A levels and that might play a role in the increased proliferation and invasion of NB cells prior to ATRA-treatment.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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