| Disease Name |
Neuroblastoma |
| Nocoding RNA Name |
T-UC.300A |
| Expression Pattern |
down-regulated |
| Species |
Homo sapiens |
| Detection Methods |
RT-PCR,Western Blot,siRNA knockdown,Cell proliferation assay etc. |
| Target |
N/A |
| Tissue |
neuroblastoma cell lines (SH-SY5Y, SK-N-BE, LAN-5) |
| Treatment |
N/A
|
| PubMed ID |
23565812 |
| Year |
2013 |
| Detail Description |
T-UC.300A, an independent transcript whose expression is down-regulated following ATRA was achieved by siRNA knockdown, resulting in the decreased viability and invasiveness of ATRA-responsive cell lines. Gene expression microarray analysis following knockdown of T-UC.300A revealed a number of genes whose expression was altered by changing T-UC.300A levels and that might play a role in the increased proliferation and invasion of NB cells prior to ATRA-treatment. |
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