| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | TSLC1-AS1 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time Quantitative PCR,siRNA knockdown,Scratch wound healing assay etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 25031725 |
| Year | 2014 |
| Detail Description | TSLC1-AS1 expression was down-regulated in tumor tissues compared with that in adjacent normal tissues, and negatively associated with the WHO criteria of the tumors. Overexpression of TSLC1-AS1 resulted in up-regulation of TSLC1 and significant inhibition of cell proliferation, migration and invasion in U87 cells, while knockdown of TSLC1-AS1 in SNB-19 cells showed the opposite effect. The expression of TSLC1-AS1 was also positively correlated with other tumor suppressors NF1, VHL, PIK3R1 and negatively correlated with the oncogene BRAF. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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