Details
Disease Name Glioma
Nocoding RNA Name UCA1
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qPCR,Flow Cytometry,Western Blot etc.
Target N/A
Tissue surgically resected glioma samples
Treatment N/A
PubMed ID 28105536
Year 2017
Detail Description LncRNA UCA1 expression in the glioma samples was obviously higher as compared with the normal brain samples, and the expression was correlated significantly with grading of the tumors. However, lncRNA UCA1 expression was not correlated with age, gender, tumor size and KPS score. After interference of UCA1 expression by siRNA transfection, the proliferation of both U251 and SHG-44 cells was inhibited, with more cells arrested in G0/G1. Moreover, cyclin D1 expression was also downregulated considerably.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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