| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-let-7 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Immunocytochemistry,transfection,WST-1 assay etc. |
| Target | N/A |
| Tissue | glioblastoma cell lines(U251 and U87) |
| Treatment | N/A |
| PubMed ID | 20607356 |
| Year | 2011 |
| Detail Description | Human glioblastoma cells (U251 or U87 cells) were transfected with let-7 miRNA and assayed for in-vitro proliferation, migration, and in-vivo tumor formation. Transfection of let-7 miRNA reduced expression of pan-RAS, N-RAS, and K-RAS in the glioblastoma cells. Let-7 miRNA also reduced the in-vitro proliferation and migration of the cells, and reduced the sizes of the tumors produced after transplantation into nude mice. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016