Details
Disease Name Infarction, Middle Cerebral Artery
Nocoding RNA Name hsa-let-7c-5p
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR,Immunohistochemistry,Western Blot,Luciferase Reporter Assay etc.
Target caspase 3
Tissue plasma
Treatment N/A
PubMed ID 25934573
Year 2015
Detail Description the content of let-7c-5p was significantly decreased in the plasma of patients with ischemic stroke as well as in experimental animals.let-7c-5p directly targeted to the 3'-untranslated region of the caspase 3 mRNA to reduce caspase 3 levels, which may underline the miRNA-modulated microglial activity.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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