| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-100 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | FGFR3 |
| Tissue | Human glioblastoma cell lines(U251 and T98G) |
| Treatment | N/A |
| PubMed ID | 26604796 |
| Year | 2015 |
| Detail Description | MiR-100 was markedly downregulated in both glioblastoma cell lines and human tumors. Overexpressing miR-100 through lentiviral transfection in U251 and T98G cells significantly inhibited cancer growth (both in vitro and in vivo) and migration and increased chemosensitivity to cisplatin and 1, 3-bis (2-chloroethyl)-l-nitrosourea, whereas downregulation of miR-100 had no effects on development of cancer. FGFR3 was directly regulated by miR-100 in glioblastoma. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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