Details
Disease Name Lesch-Nyhan Syndrome
Nocoding RNA Name hsa-miR-106a
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods qPCR etc.
Target N/A
Tissue fibroblasts
Treatment N/A
PubMed ID 23804752
Year 2013
Detail Description Using fibroblasts isolated several controls and several Lesch-Nyhan syndrome (LNS) patients, we examined the expression of each of the five microRNAs that constitute the miR-17 family cluster. Data show that while miR-17 expression is significantly increased, miR-20a and miR-106a expression is significantly reduced in fibroblasts derived from LNS patients comparatively to control subjects.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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