Details
Disease Name Astrocytoma
Nocoding RNA Name hsa-miR-106a-5p
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Quantitative Real-time PCR,Luciferase Reporter Assay,Western Blot etc.
Target FASTK
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 24013584
Year 2013
Detail Description we found that the downregulation of miR-106a-5p in astrocytomas is associated with poor prognosis.We then performed bioinformatics analysis based on multiple target prediction algorithms to obtain candidate target genes that were further validated by computational predictions, western blot analysis, quantitative real-time PCR, and the luciferase reporter assay. Fas-activated serine/threonine kinase (FASTK) was identified as a direct target of miR-106a-5p.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016