| Details |
| Disease Name | Alzheimer Disease |
| Nocoding RNA Name | hsa-miR-107 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray,Northern Blot,Western Blot,Luciferase Reporter Assay etc. |
| Target | BACE1 |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 18234899 |
| Year | 2008 |
| Detail Description | BACE1 mRNA levels tended to increase as miR-107 levels decreased in the progression of AD.Cell culture reporter assays performed with a subset of the predicted miR-107 binding sites indicate the presence of at least one physiological miR-107 miRNA recognition sequence in the 3 -UTR of BACE1 mRNA.MiR-107 may be involved in accelerated disease progression through regulation of BACE1. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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