Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-10b
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Taqman miRNA reverse transcription,Invasion assay etc.
Target TP53
Tissue glioblastoma cell lines
Treatment N/A
PubMed ID 23034333
Year 2012
Detail Description Expression of miR-10b is elevated in invasive mesenchymal subtype-like U87-2M1 glioma cells, silencing of miRNA-10b by baculoviral decoy vectors in a glioma cell line resembling the mesenchymal subtype of GBM reduces its growth, invasion and angiogenesis while promoting apoptosis in vitro. Identification of TP53, FOXO3, CYLD, NOTCH1, PTCH1 and PAX6 as targets of miR-10b.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016