| Details |
| Disease Name | Glioma |
| Nocoding RNA Name | hsa-miR-10b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,cell viability and caspase assays,Luciferase Reporter Assay etc. |
| Target | BCL2L11 |
| Tissue | glioma cell lines |
| Treatment | N/A |
| PubMed ID | 21471404 |
| Year | 2011 |
| Detail Description | inhibition of miR-10b, a miRNA not expressed in human brain and strongly upregulated in both lowgrade and high-grade gliomas, reduces glioma cell growth by cell-cycle arrest and apoptosis. These cellular responses are mediated by augmented expression of the direct targets of miR-10b, including BCL2L11/Bim,TFAP2C/AP-2g, CDKN1A/p21, and CDKN2A/p16, which normally protect cells from uncontrolled growth. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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