| Disease Name |
Multiple Sclerosis, Relapsing-Remitting |
| Nocoding RNA Name |
hsa-miR-124 |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
RT-PCR,Luciferase Reporter Assay etc. |
| Target |
AMPA2 |
| Tissue |
brain |
| Treatment |
N/A
|
| PubMed ID |
23595422 |
| Year |
2013 |
| Detail Description |
Compared to myelinated hippocampi, 4 miRNAs were significantly decreased and 7 miRNAs were significantly increased in demyelinated hippocampus,Transfection of primary neurons with an miR-124 mimic led to a significant increase in levels of miR-124 and a significant decrease in AMPA1, AMPA2, and AMPA3 mRNA levels when compared to neurons that were not transfected with the miR-124 mimic. |
|