Details
Disease Name Multiple Sclerosis, Relapsing-Remitting
Nocoding RNA Name hsa-miR-124
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods RT-PCR,Luciferase Reporter Assay etc.
Target AMPA2
Tissue brain
Treatment N/A
PubMed ID 23595422
Year 2013
Detail Description Compared to myelinated hippocampi, 4 miRNAs were significantly decreased and 7 miRNAs were significantly increased in demyelinated hippocampus,Transfection of primary neurons with an miR-124 mimic led to a significant increase in levels of miR-124 and a significant decrease in AMPA1, AMPA2, and AMPA3 mRNA levels when compared to neurons that were not transfected with the miR-124 mimic.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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