| Details |
| Disease Name | Medulloblastoma |
| Nocoding RNA Name | hsa-miR-124 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,Luciferase Reporter Assay and Western Blot etc. |
| Target | CDK6 |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 18607543 |
| Year | 2008 |
| Detail Description | Expression of miR-124 was significantly decreased in Daoy, D283 Med and D341 Med compared to normal adult cerebellar RNA.miR-124 in medulloblastoma, we also examined expression in a panel of primary cell explants we have established from patient tissue and previously described. miR-124 expression was indeed decreased in the primary cells, although not to the same extent as the cell lines.Functional association between miR-124 and CDK6 in medulloblastoma was established using luciferase assays. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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