Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-124
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Immunohistochemistry,immunofluorescence assays etc.
Target MAPK14
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 24954504
Year 2015
Detail Description miR-124 expression is negatively correlated with a hypoxic gene signature in glioblastoma patient samples, suggesting that low miR-124 levels contribute to pro-survival adaptive pathways in this disease.miR-124 exerts this phenotype in part by directly regulating TEAD1, MAPK14/p38α and SERP1, factors involved in cell proliferation and survival under stress.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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