| Disease Name |
Medulloblastoma |
| Nocoding RNA Name |
hsa-miR-1260 |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
miRNA array,Real-time RT-PCR etc. |
| Target |
N/A |
| Tissue |
medulloblastoma cell lines |
| Treatment |
N/A
|
| PubMed ID |
25576913 |
| Year |
2015 |
| Detail Description |
Comparative analysis of the respective miRNA profiles revealed that among 39 highly regulated miRNAs, a subset of miRNAs including miR-1280 and miR-1260 was concordantly regulated by PDGFRβ and c-MYC. Next we analyzed the expression levels of miR-1280 and miR-1260 (two highly regulated miRNAs by both PDGFR and c-MYC) by realtime RT-PCR upon knockdown of PDGFRα and PDGFRβ, each separately or both combined, in three MB cell lines (Daoy, D283, and D425). |
|