Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-127-3p
Expression Pattern differentially expressed
Species Homo sapiens
Detection Methods Luciferase Reporter Assay,Western Blot,microarray etc.
Target 7-Sep
Tissue glioblastoma cell lines
Treatment N/A
PubMed ID 24604520
Year 2014
Detail Description a positive correlation between the levels of miR-127-3p and the cell migration and invasion abilities in several human GBM cell lines. We showed that miR-127-3p promoted cell migration and invasion of GBM cells using in vitrocell lines and in vivomouse models. We identified SEPT7, a known tumor-suppressor gene that has been reported to suppress GBM cell migration and invasion, as a direct target of miR-127-3p.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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