Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-128
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Real-time PCR,Luciferase Reporter Assay,Western Blot etc.
Target Rap1B
Tissue Human glioblastoma cell lines (U87MG)
Treatment temozolomide
PubMed ID 25017996
Year 2014
Detail Description expression of miR-128 and miR-149 was downregulated in glioblastoma, and their overexpression inhibited the invasion of glioblastoma cells by targeting Rap1B-mediated cytoskeletal and related molecular alterations. Moreover, miR-128 and miR-149 enhanced the chemosensitivity of glioblastoma cells to TMZ.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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