| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-128 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Northern Blot,Western Blot etc. |
| Target | E2F-3a |
| Tissue | glioblastoma cell lines |
| Treatment | N/A |
| PubMed ID | 19941032 |
| Year | 2010 |
| Detail Description | Both glioma and glioblastoma multiforme(GBM) cell lines exhibited a significant down-regulation of miRNA-128 ranging from an average of 0.24- to 0.54-fold compared to primary human neural cell controls.Three bioinformatics-verified miRNA-128 targets, angiopoietin-related growth factor protein 5 (ARP5; ANGPTL6), a transcription suppressor that promotes stem cell renewal and inhibits the expression of known tumor suppressor genes involved in senescence and differentiation,Bmi-1, and a transcription factor critical for the control of cell-cycle progression, E2F-3a, were found to be up-regulated. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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