In a panel of patient glioblastoma specimens, Bmi-1 expression was significantly up-regulated and miR-128 was down-regulated compared with normal brain.miR-128 caused a striking decrease in expression of the Bmi-1 oncogene, by direct regulation of the Bmi-1 mRNA 3-untranslated region, through a single miR-128 binding site.
NSDNA: The Nervous System Disease NcRNAome Atlas
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