Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-128-2
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods microarray,Quantitative RT-PCR etc.
Target Bmi-1
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 19010882
Year 2008
Detail Description In a panel of patient glioblastoma specimens, Bmi-1 expression was significantly up-regulated and miR-128 was down-regulated compared with normal brain.miR-128 caused a striking decrease in expression of the Bmi-1 oncogene, by direct regulation of the Bmi-1 mRNA 3-untranslated region, through a single miR-128 binding site.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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