| Detail Description |
We performed a genome-wide survey of 427 mature miRNAs in a series of 90 primary human medulloblastomas and 10 normal human cerebella ( five fetal and five adult). Notably, components of miR-17/92, including miR-18a, miR-19b, and miR-20a, as well as the paralogous miR-106a (miR-106a/363 cluster) clustered together, were expressed at low levels in the normal cerebella and showed considerably higher levels of expression in most medulloblastomas. |