| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-130b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time qPCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | SAV1 |
| Tissue | Human glioblastoma cell lines(SNB19, U87MG, LN444, LN18 and U251MG) |
| Treatment | N/A |
| PubMed ID | 26241672 |
| Year | 2015 |
| Detail Description | miR-130b directly repressed MST1 and SAV1 expression in human glioblastoma cells. Overexpression of miR-130b induced hyperactivation of the YAP/TAZ and enhanced expression of the Hippo signaling downstream genes CTGF and the pluripotency associated markers, including CD133, SOX2, Nanog, MYC and BMI1, leading to promotion of glioblastoma stem cell phenotype. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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