Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-130b-3p
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Fluorescent immunohistochemistry etc.
Target PTEN
Tissue Human glioblastoma cell lines(A172)
Treatment radiation
PubMed ID 26622832
Year 2015
Detail Description When the expression of miRNAs was examined in GSCs irradiated at 60 Gy using the human GBM A172 cell line, the expression of PTEN-targeting miR-17-5p, -19a-3p, -19b-3p, -21-5p, -130b-3p, -221-3p and -222-3p was significantly higher in irradiated GSCs than in non-irradiated cells, and the PTEN expression levels, as revealed by immunostaining, were lower in the irradiated GSCs than in the non-irradiated cells.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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