Details
Disease Name Chorea
Nocoding RNA Name hsa-miR-132
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR etc.
Target REST
Tissue brain
Treatment N/A
PubMed ID 18082412
Year 2008
Detail Description Here, we show that expression of a number of neuronal-specific microRNAs is also dysregulated in HD tissues, probably as a result of increased repression by REST. This phenomenon is observed in both murine models of HD and in the brains of human HD sufferers. MicroRNA loss is reflected in increased levels of a number of target messenger RNAs.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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