Details
Disease Name Epilepsy, Temporal Lobe
Nocoding RNA Name hsa-miR-134
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time qPCR etc.
Target LIMK1
Tissue brain
Treatment N/A
PubMed ID 22683779
Year 2012
Detail Description We next analyzed surgically obtained temporal lobe material from individuals with pharmacoresistent temporal lobe epilepsy(TLE). We detected higher levels(P= 0.029) of mature miR-134 in the TLE specimens compared to autopsy control samples from people who died of causes unrelated to neurological disease. This difference was not an artifact of postmortem delay. Protein concentrations of LIMK1 were lower (P= 0.039) in individuals with TLE compared to the autopsy controls.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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