| Details |
| Disease Name | Oligodendroglioma |
| Nocoding RNA Name | hsa-miR-137 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | RT-PCR, Luciferase Reporter Assay,Western Blot etc. |
| Target | CSE1L |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 23252729 |
| Year | 2013 |
| Detail Description | we demonstrate that miR-137 expression is significantly downregulated in a cohort of 35 oligodendroglial tumors and nine glioma cell lines compared with normal brains.Luciferase reporter assay demonstrated that miR-137 negatively regulates CSE1L by interaction between miR-137 and complementary sequences in the 3′UTR of CSE1L. Immunohistochemistry revealed that CSE1L is upregulated in oligodendroglial tumors. Knockdown of CSE1L resulted in similar outcomes as overexpressing miR-137 in oligodendroglioma cells and glioblastoma cells. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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