Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-138
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Real-time PCR, Luciferase Reporter Assay,Immunohistochemistry,Western Blot etc.
Target E2F3
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 23707559
Year 2013
Detail Description miRNA-138 is reduced in both GBM clinical specimens and cell lines, and is effective to inhibit EZH2 expression.Mechanism investigation reveals that miRNA-138 acquires tumor inhibition through directly targeting EZH2, CDK6, E2F2 and E2F3.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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