| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-143 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | next generation sequencing,RT-PCR etc. |
| Target | N/A |
| Tissue | glioblastoma cell lines |
| Treatment | N/A |
| PubMed ID | 21211035 |
| Year | 2011 |
| Detail Description | After miRNA sequencing and data analysis, we found 105 precursor microRNAs (corresponding to 95 mature miRNAs) that were changed>2 fold between SOX2 knockdown and SOX2-MOCK transfected LN229 cells.Six microRNAs including miR-145, -143, -145*, -143*, -253-5p and miR-452,were up regulated after SOX2 knockdown and the rest were down regulated when SOX2 was knocked down. We picked 6 miRNAs to confirm the next generation data using RT-PCR. We confirmed that miR-143 and miR-145 were up regulated after SOX2 knockdown and that miR-146a, -25, -20b and miR-9-1 were down regulated after SOX2 knockdown. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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