| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-144-3p |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | RT-qPCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | MET |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 26250785 |
| Year | 2015 |
| Detail Description | miR-144-3p level was significantly down-regulated in glioma compared with the non-neoplastic brain tissues, and decreased with ascending grades.miR-144-3p potently repressed GBM cell proliferation and invasion via suppressing MET in vitro and in vivo. In addition, our results showed no difference in malignancy inhibition induced by miR-144-3p in GBM cells with different PTEN phenotypes. miR-144-3p inhibited several survival signaling pathways by targeting MET independent of PTEN status in GBM cells. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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