| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-145 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,Luciferase Reporter Assay,Immunoblotting Analysis etc. |
| Target | JAM-A |
| Tissue | brain |
| Treatment | N/A |
| PubMed ID | 26374689 |
| Year | 2015 |
| Detail Description | Using patient-derived glioblastoma CSCs, we confirmed that JAM-A is suppressed by miR-145. CSCs expressed low levels of miR-145, and its introduction decreased self-renewal through reductions in AKT signaling and stem cell marker (SOX2, OCT4, and NANOG) expression; JAM-A overexpression rescued these effects. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016