| Disease Name |
Glioma |
| Nocoding RNA Name |
hsa-miR-145 |
| Expression Pattern |
down-regulated |
| Species |
Homo sapiens |
| Detection Methods |
Real-time PCR,Western Blot,Luciferase Reporter Assay,Methylation assays etc. |
| Target |
ADD3 |
| Tissue |
brain(glioma tissue) |
| Treatment |
N/A
|
| PubMed ID |
23814265 |
| Year |
2013 |
| Detail Description |
Our study demonstrates that miR-145 has a tumor-suppressive function in glioblastoma in that it reduces proliferation,adhesion,and invasion of glioblastomacells,apparently by suppressing the activity of oncogenic proteins Sox9 and ADD3. |
|