| Disease Name |
Alzheimer Disease |
| Nocoding RNA Name |
hsa-miR-146a |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
miRNA array,Western Blot,Luciferase Reporter Assay etc. |
| Target |
CFH |
| Tissue |
brain(Human neural cells) |
| Treatment |
N/A
|
| PubMed ID |
19540598 |
| Year |
2009 |
| Detail Description |
These data suggest that (1) as in AD brain,NF-jB-sensitive,miRNA-146a mediated,modulation of CFH gene expression may contribute to inflammatory responses in aluminum-stressed HN cells,and (2) underscores the potential of nanomolar aluminum to drive genotoxic mechanisms characteristic of neurodegenerative disease processes. |
|