| Details |
| Disease Name | Alzheimer Disease |
| Nocoding RNA Name | hsa-miR-146a |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | miRNA array,Northern Blot,Luciferase Reporter Assay,Western Blot etc. |
| Target | IRAK-1 |
| Tissue | brain(Human astroglial cells) |
| Treatment | N/A |
| PubMed ID | 20937840 |
| Year | 2010 |
| Detail Description | These data suggest a significantly independent regulation of IRAK-1 and IRAK-2 in AD and in IL-1β+Aβ42 peptide-stressed HAG cells and that an inducible,NF-B-sensitive,miRNA-146a-mediated downregulation of IRAK-1 coupled to an NF-B-induced up-regulation of IRAK-2 expression drives an extensively sustained inflammatory response. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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