Details
Disease Name Huntington Disease
Nocoding RNA Name hsa-miR-146b
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Luciferase Reporter Assay, RT-PCR and Western Blot etc.
Target p65
Tissue STHdh Q111/Hdh Q111 cell line
Treatment N/A
PubMed ID 21887328
Year 2011
Detail Description Among the altered miRNAs, miR-146a is down regulated among the altered miRNAs, miR-146a is down regulated,we show by luciferase reporter assays and real time PCR that decreased miR-146a expression in STHdhQ111/HdhQ111 cells is due to decreased expression and activity of p65 subunit of NFkB (RelA/NFkB).

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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