| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-148a |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative RT-PCR,Cell transfections,Luciferase Reporter Assay etc. |
| Target | MIG6 |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 24425048 |
| Year | 2014 |
| Detail Description | miR-148a expression was elevated in human glioblastoma specimens, cell lines, and stem cells (GSC) compared with normal human brain and astrocytes. High levels were a risk indicator for glioblastoma patient survival.Two direct targets of miR-148a were identified, the EGF receptor (EGFR) regulator MIG6 and the apoptosis regulator BIM, which rescue experiments showed were essential to mediate the oncogenic activity of miR-148a. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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