| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-152 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative RT-PCR,transfection,Luciferase Reporter Assay etc. |
| Target | KLF4 |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 25218589 |
| Year | 2014 |
| Detail Description | miR-152 was down-regulated in human glioblastoma stem cells(GSCs).Restoring the expression of miR-152 dramatically reduced the cell proliferation, cell migration and invasion as well as inducing apoptosis. Mechanistic investigations defined Kruppel-like factor 4 (KLF4) as a direct and functional downstream target of miR-152, which was involved in the miR-152-mediated tumor-suppressive effects in GSCs. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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