Details
Disease Name Multiple Sclerosis, Relapsing-Remitting
Nocoding RNA Name hsa-miR-17
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Quantitative Real-time RT-PCR etc.
Target TGFBR2
Tissue blood(Peripheral blood mononuclear cells)
Treatment N/A
PubMed ID 24901013
Year 2014
Detail Description we validated upregulation of miR-17 expression in RRMS patients,Interestingly, natalizumab treatment decreased miR-17 expression in MS patients,Downregulation of miR-17 was associated with upregulation of PTEN, BIM, E2F1, and p21 target genes,confirmin vitrothe link between miR-17 and TGFBR2 expressions.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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