| Disease Name |
Glioblastoma |
| Nocoding RNA Name |
hsa-miR-17-5p |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR,Fluorescent immunohistochemistry etc. |
| Target |
PTEN |
| Tissue |
Human glioblastoma cell lines(A172) |
| Treatment |
radiation
|
| PubMed ID |
26622832 |
| Year |
2015 |
| Detail Description |
When the expression of miRNAs was examined in GSCs irradiated at 60 Gy using the human GBM A172 cell line, the expression of PTEN-targeting miR-17-5p, -19a-3p, -19b-3p, -21-5p, -130b-3p, -221-3p and -222-3p was significantly higher in irradiated GSCs than in non-irradiated cells, and the PTEN expression levels, as revealed by immunostaining, were lower in the irradiated GSCs than in the non-irradiated cells. |
|