| Details |
| Disease Name | Lesch-Nyhan Syndrome |
| Nocoding RNA Name | hsa-miR-181a |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | miRNA microarray,qPCR,Luciferase Reporter Assay etc. |
| Target | En1/2 |
| Tissue | fibroblasts |
| Treatment | N/A |
| PubMed ID | 22042773 |
| Year | 2012 |
| Detail Description | Results from that preliminary examination identified several miRNAs that suggested altered expression of >1.5-fold (P<0.05) in the LND cells compared with that of the normal control fibroblast culture, including mir-138-1*, miR181a, miR-601 and miR-765.miR181a acts on En1/2 and Lmx1a gene expression by interacting with the 3′UTR binding sites of the genes, as expected for typical microRNAs. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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