Details
Disease Name Astrocytoma
Nocoding RNA Name hsa-miR-181b-5p
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Quantitative Real-time PCR,Luciferase Reporter Assay etc.
Target NOVA1
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 25299073
Year 2014
Detail Description To assess the expression of miR-181b-5p in astrocytomas, a qRT-PCR analysis was performed on 25 NAT samples and 90 astrocytoma tissue samples. The results showed that the expression of miR-181b-5p was consistently lower in the astrocytoma tissues compared with the NAT samples.These results strongly demonstrate that NOVA1 is a target gene of miR-181b-5p, which directly recognizes the 39-UTR of the NOVA1 transcript to downregulate its expression.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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