| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-181c |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time PCR etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | temozolomide |
| PubMed ID | 20353279 |
| Year | 2010 |
| Detail Description | we examined the expression levels of selected microRNAs in 22 primary glioblastomas and six specimens of adult brain tissue by real-time PCR method. MiR-221 (p=0.016), miR-222 (p=0.038), miR-181b (p=0.036), miR-181c (p=0.043) and miR-128a (p=0.001) were significantly down-regulated in glioblastomas. The most significant change was observed for up-regulation in miR-21 expression in glioblastomas (p<0.001). MiR-181b and miR-181c were significantly down-regulated in patients who responded to temozolomide (RT/TMZ) (p=0.016; p=0.047, respectively) in comparison to patients with progredient disease. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016