NSDNA: The Nervous System Disease NcRNAome Atlas

Details

Disease Name	Ataxia Telangiectasia
Nocoding RNA Name	hsa-miR-181c
Expression Pattern	differentially expressed
Species	Homo sapiens
Detection Methods	qRT-PCR etc.
Target	N/A
Tissue	lymphoblastoid cells
Treatment	N/A
PubMed ID	18674748
Year	2008
Detail Description	15 miRNAs with recessive patterns where the IR-induced expression patterns were similar between noncarriers and AT carriers but were significantly different (p<0.001) from AT patients. Among these 15 miRNAs are MIRN181A2 and MIRN195, which are known to play a role in tumorigenesis and regulation of stress-induced cell growth.In addition, there were seven miRNAs that exhibit dominant IR-induced patterns where the profiles were similar between carriers and AT patients but were significantly different (p<0.001) from noncarriers.

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