Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-182
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods RT-qPCR,Luciferase Reporter Assay etc.
Target Bcl2L12
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 25838542
Year 2015
Detail Description GBM tumors carrying p53 mutations showed elevated levels of miR-182 compared with those with wild-type p53.miR-182, but not other members of the miR-183-96-182 cluster transcribed from the same polycistronic transcript, directly binds to the 3′UTR of Bcl2L12 and represses its mRNA and protein expression.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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